Original Papers

• 1.

  Sakai M, Hayakawa Y, Funada Y, Ando T, Fukusaki E, Bamba T.
  Development of a split-flow system for high precision variable sample introduction in supercritical fluid chromatography.
  J Chromatogr A. 1515，218-231.

• 2.

  Takeo E, Sasano R, Shimma S, Bamba T, Fukusaki E.
  Solid-phase analytical derivatization for gas-chromatography-mass-spectrometry-based metabolomics.
  J Biosci Bioeng. 124(6)，700-706.

• 3.

  An PNT, Shimaji K, Tanaka R, Yoshida H, Kimura H, Fukusaki E, Yamaguchi M.
  Epigenetic regulation of starvation-induced autophagy in Drosophila by histone methyltransferase G9a.
  Sci Rep. 7(1)，7343.

• 4.

  Regestein Née Meissner L, Arndt J, Palmen TG, Jestel T, Mitsunaga H, Fukusaki E, Büchs J.
  Investigation of poly(γ-glutamic acid) production via online determination of viscosity and oxygen transfer rate in shake flasks.
  J Biol Eng. 11，23.

• 5.

  Nitta K, Laviña WA, Pontrelli S, Liao JC, Putri SP, Fukusaki E.
  Orthogonal partial least squares/projections to latent structures regression-based metabolomics approach for identification of gene targets for improvement of 1-butanol production in Escherichia coli.
  J Biosci Bioeng. 124(5)，498-505.

• 6.

  Taniguchi M, Konya Y, Nakano Y, Fukusaki E.
  Investigation of storage time-dependent alterations of enantioselective amino acid profiles in kimchi using liquid chromatography-time of flight mass spectrometry.
  J Biosci Bioeng. 124(4)，414-418.

• 7.

  Matsuo T, Tsugawa H, Miyagawa H, Fukusaki E.
  Integrated strategy for unknown EI-MS identification using quality control calibration curve, multivariate analysis, EI-MS spectral database, and retention index prediction.
  Anal Chem. 89(12)，6766-6773.

• 8.

  Ohtake T, Pontrelli S, Laviña WA, Liao JC, Putri SP, Fukusaki E.
  Metabolomics-driven approach to solving a CoA imbalance for improved 1-butanol production in Escherichia coli.
  Metab Eng. 41，135-143.

• 9.

  PNT An, M Yamaguchi, E Fukusaki
  Metabolic profiling of Drosophila melanogaster metamorphosis: a new insight into the central metabolic pathways
  Metabolomics 13 (3), 29

• 10.

  Ogawa T, Izumi Y, Kusumoto K, Fukusaki E, Bamba T.
  Wide target analysis of acylglycerols in miso (Japanese fermented soybean paste) by supercritical fluid chromatography coupled with triple quadrupole mass spectrometry and the analysis of the correlation between taste and both acylglycerols and free fatty acids.
  Rapid Commun Mass Spectrom. 31(11),928-936.

• 11.

  Sakanaka A, Kuboniwa M, Hashino E, Bamba T, Fukusaki E, Amano A.
  Distinct signatures of dental plaque metabolic byproducts dictated by periodontal inflammatory status.
  Sci Rep. 7,42818.

• 12.

  Sano T, Okabe R, Iwahashi M, Imagi J, Sato T, Yamashita T, Fukusaki E, Bamba T.
  Effect of Furan Fatty Acids and 3-Methyl-2,4-Nonanedione on Light-Induced Off-Odor in Soybean Oil.
  J Agric Food Chem.65(10),2136-2140.

• 13.

  Nagao H, Nishizawa H, Bamba T, Nakayama Y, Isozumi N, Nagamori S, Kanai Y, Tanaka Y, Kita S, Fukuda S, Funahashi T, Maeda N, Fukusaki E, Shimomura
  Increased Dynamics of Tricarboxylic Acid Cycle and Glutamate Synthesis in Obese Adipose Tissue: In vivo Metabolic Turnover Analysis.
  J Biol Chem. 292(11),4469-4483.

• 14.

  Takeda H, Izumi Y, Tomita A, Koike T, Shiomi M, Fukusaki E, Matsuda F, Bamba T.
  Lipoprotein profiling methodology based on determination of apolipoprotein concentration.
  Bioanalysis. 9(1),9-19.

• 15.

  Jumhawan U, Yamashita T, Ishida K, Fukusaki E, Bamba T.
  Simultaneous profiling of 17 steroid hormones for the evaluation of endocrine-disrupting chemicals in H295R cells.
  Bioanalysis. 9(1),67-69.

• 16.

  Harada R, Yuzuki M, Ito K, Shiga K, Bamba T, Fukusaki E.
  Influence of yeast and lactic acid bacterium on the constituent profile of soy sauce during fermentation.
  J Biosci Bioeng. 123(2),203-208.

• 17.

  Konya Y, Taniguchi M, Fukusaki E.
  Novel high-throughput and widely-targeted liquid chromatography-time of flight mass spectrometry method for D-amino acids in foods.
  J Biosci Bioeng. 123(1),126-133.

• 18.

  Hirokawa Y, Dempo Y, Fukusaki E, Hanai T.
  Metabolic engineering for isopropanol production by an engineered cyanobacterium, Synechococcus elongatus PCC 7942, under photosynthetic conditions.
  J Biosci Bioeng. 123(1),39-45.

• 19.

  Miyauchi S, Yonetani T, Yuki T, Tomio A, Bamba T, Fukusaki E.
  Quality evaluation of green tea leaf cultured under artificial light condition using gas chromatography/mass spectrometry.
  J Biosci Bioeng. 123(2),197-202.

• 20.

  Nakano Y, Konya Y, Taniguchi M, Fukusaki E.
  Development of a liquid chromatography-tandem mass spectrometry method for quantitative analysis of trace D-amino acids.
  J Biosci Bioeng. 123(1),134-138.

Original Papers

• 1.

  C.Nath, S., Nagamori, E., Horie, M. and Kino-oka, M.
  Culture medium refinement by dialysis for the expansion of human induced pluripotent stem cells in suspension culture.
  Bioproc. Biosyst. Eng. 40, 123-131.

• 2.

  Yamasaki-Yashiki, S., Sawada, H., Kino-oka, M. and Katakura, Y.
  Analysis of gene expression profiles of lactobacillus paracasei induced by direct contact with Saccharomyces Cerevisiae through recognition of yeast mannan.
  Biosci. Microbiota. Food Health. 36, 17-25.

• 3.

  Li, M., Nagamori, E. and Kino-oka, M.
  Disruption of myoblast alignment by highly motile rhabdomyosarcoma cell in tissue structure.
  J. Biosci. Bioeng. 123, 259-264.

• 4.

  Kim, M.-H., Sugawara, Y., Fujinaga, Y. and Kino-oka, M.
  Botulinum hemagglutinin-mediated selective removal of cells deviating from the undifferentiated state in hiPSC Colonies.
  Sci. Rep. 7, 93.

• 5.

  Li, M. and Kino-oka, M.
  Degradation of endothelial network in disordered tumor-containing cell sheet.
  J. Biosci. Bioeng. 123, 748-753.

• 6.

  Sonoi, R., Kim, M.-H., Yamada, K. and Kino-oka, M.
  Phenotypic heterogeneity of human retinal pigment epithelial cells in passaged cell populations.
  J. Biosci. Bioeng. 124, 227-233.

• 7.

  Wongin, S., Ogawa, Y., Kim, M.-H., Viravaidya-Pasuwat, K. and Kino-oka, M.
  Chondrogenesis and hypertrophy in response to aggregate behaviors of human mesenchymal stem cells on a dendrimer-immobilized surface.
  Biotechnol. Lett. 39, 1253-1261.

• 8.

  C.Nath, S., Horie, M., Nagamori, E. and Kino-oka, M.
  Size- and time-dependent growth properties of human induced pluripotent stem cells in the culture of single aggregate.
  J. Biosci. Bioeng. 124, 469-475.

• 9.

  Kim, M.-H., Inamori, M., Akechi, M., Abe, H., Yagi, Y. and Kino-oka, M.
  Development of an automated chip culture system with integrated on-line monitoring for maturation culture of retinal pigment epithelial cells.
  AIMS Bioengineering 4, 402-417.

Reviews

• 1.

  Galvanauskas, V., Grincas, V., Simutis, R., Kagawa, Y. and Kino-oka, M.
  Current state and perspectives in modeling and control of human pluripotent stem cell expansion processes in stirred-tank bioreactors.
  Biotechnol. Prog. 33, 355-364.

Original Papers

• 1.

  Torisu T, Maruno T, Hamaji Y, Ohkubo T, Uchiyama S.
  Synergistic effect of cavitation and agitation on protein aggregation.
  J. Pharm. Sci. 106, 521-529.

• 2.

  Krayukhina E, Noda M, Ishii K, Maruno T, Wakabayashi H, Tada M, Suzuki T, Ishii-Watabe A, Kato M, Uchiyama S.
  Analytical ultracentrifugation with fluorescence detection 1 system reveals differences in complex formation between recombinant human TNFα and different biological TNFα antagonists in various environments.
  mAbs 9, 664-679.

• 3.

  Kagami Y, Uchiyama S, Kato H, Okada Y, Seto M, Kinoshita T.
  Establishment of cell lines from adult T-cell leukemia cells dependent on negatively charged polymers.
  J. Clin. Exp. Hematop. 57, 9-14.

• 4.

  Torisu T, Maruno T, Yoneda S, Hamaji Y, Honda S, Ohkubo T, Uchiyama S.
  Friability testing as a new stress-stability assay for biopharmaceuticals.
  J. Pharm. Sci. 106, 2966-2978.

• 5.

  Shinozaki N, Hashimoto R, Fukui K, Uchiyama S.
  Efficient generation of single domain antibodies with high affinities and enhanced thermal stabilities.
  Sci. Rep. 7, 5794.

• 6.

  Phengchat R, Takata H, Uchiyama S, Fukui K.
  Calcium depletion destabilises kinetochore fibres by the removal of CENP-F from the kinetochore.
  Sci. Rep. 7, 7335.

• 7.

  Ishii-Watabe A, Shibata H, Harazono A, Hyuga M, Kiyoshi M, Saitoh S, Iwura T, Torisu T, Goda Y, Uchiyama S.
  Recent topic in research on characterization and quality control of biopharmaceuticals in Japan.
  J. Pharm. Sci. 106, 3431-3437.

• 8.

  Poonperm R, Takata H, Uchiyama S, Fukui K.
  Interdependency and Phosphorylation of KIF4 and Condensin I are essential for Organization of Chromosome Scaffold.
  PLoS One 12, e0183298.

• 9.

  Wang W, Marchetti R, Prisic S, Ishii K, Arai Y, Ohta I, Inuki S, Uchiyama S, Silipo A, Molinaro A, Husson RN, Fukase K, Fujimoto Y.
  A Comprehensive Study of Interaction between Peptidoglycan Fragments and Extracelluar Domain of Mycobacterium tuberculosis Ser/Thr Kinase PknB.
  ChemBioChem. 18, 1-6.

• 10.

  Yanaka S, Yamazaki T, Yogo R, Noda M, Uchiyama S, Yagi H, Kato K.
  NMR Detection of Semi-Specific Antibody Interactions in Serum Environments.
  Molecules 27, E1619.

• 11.

  Sasano Y, Kariya T, Usugi S, Sugiyama M, Harashima S.
  Molecular breeding of Saccharomyces cerevisiae with high RNA content by harnessing essential ribosomal RNA transcription regulator.
  AMB Express 7, 32.

Original Papers

• 1.

  Nong QD, Mohamad Ishak NS, Matsuura T, Kato Y, Watanabe H.
  Mapping the expression of the sex determining factor Doublesex1 in Daphnia magna using a knock-in reporter.
  Sci Rep 7, 13521.

• 2.

  Mohamad Ishak NS, Nong QD, Matsuura T, Kato Y, Watanabe H.
  Co-option of the bZIP transcription factor Vrille as the activator of Doublesex1 in environmental sex determination of the crustacean Daphnia magna.
  PLoS Genet 13, e1006953.

• 3.

  Matsuura T, Tanimura N, Hosoda K, Yomo T, Shimizu Y.
  Reaction dynamics analysis of a reconstituted Escherichia coli protein translation system by computational modeling.
  Proc Natl Acad Sci U S A 114, E1336-E1344.

• 4.

  Manakul P, Peerakietkhajorn S, Matsuura T, Kato Y, Watanabe H.
  Effects of symbiotic bacteria on chemical sensitivity of Daphnia magna.
  Mar Environ Res 128, 70-75.

• 5.

  Kumagai H, Nakanishi T, Matsuura T, Kato Y, Watanabe H.
  CRISPR/Cas-mediated knock-in via non-homologous end-joining in the crustacean Daphnia magna.
  PLoS One 12, e0186112.

• 6.

  Kumagai H, Matsuura T, Kato Y, Watanabe H.
  Development of a bicistronic expression system in the branchiopod crustacean Daphnia magna.
  Genesis 55, e23083.

Original Papers

• 1.

  Mochida, K., Sakurai, T., Seki, H., Yoshida, T., Takahagi, K., Sawai, S., Uchiyama, H., Muranaka, T. and Saito, K.
  Draft genome assembly and annotation of Glycyrrhiza uralensis, a medicinal legume.
  Plant J. 89, 181-194.

• 2.

  Vo, N.N., Fukushima, E.O. and Muranaka, T.
  Structure and hemolytic activity relationships of triterpenoid saponins and sapogenins.
  J. Nat. Med. 71, 50-58.

• 3.

  Kobayashi, K., Kobayashi, K., Yamaguchi, H., Inoue-Miyagi, Y., Takagi, K., Fushihara, K., Seki, H., Suzuki, M., Nagata, N. and Muranaka, T.
  Platform for “chemical metabolic switching” to increase sesquiterpene content in plants.
  Plant Biotechnol. 34, 65-69.

• 4.

  Yasumoto, S., Seki, H., Shimizu, Y., Fukushima, E.O. and Muranaka, T.
  Functional characterization of CYP716 family P450 enzymes in triterpenoid biosynthesis in tomato.
  Front. Plant Sci. 8, 21.

• 5.

  Tamura, K., Seki, H., Suzuki, H., Kojoma, M., Saito, K. and Muranaka, T.
  CYP716A179 functions as a triterpene C-28 oxidase in tissue-cultured stolons of Glycyrrhiza uralensis.
  Plant Cell Rep. 36, 437-445.

• 6.

  Robertlee, J., Kobayashi, K., Suzuki, M. and Muranaka, T.
  AKIN10, a representative Arabidopsis SNF1-related protein kinase 1 (SnRK1), phosphorylates and downregulates plant HMG-CoA reductase.
  FEBS Lett. 591, 1159-1166.

• 7.

  Tamura, K., Teranishi, Y., Ueda, S., Suzuki, H., Kawano, N., Yoshimatsu, K., Saito, K., Kawahara, N., Muranaka, T. and Seki, H.
  Cytochrome P450 monooxygenase CYP716A141 is a unique β-amyrin C-16β oxidase involved in triterpenoid saponin biosynthesis in Platycodon grandiflorus.
  Plant Cell Physiol. 58, 874-884.

• 8.

  Nakayasu, M., Umemoto, N., Ohyama, K., Fujimoto, Y., Lee, H.J., Watanabe, B., Muranaka, T., Saito, K., Sugimoto, Y. and Mizutani, M.
  A dioxygenase catalyzes steroid 16α-hydroxylation in steroidal glycoalkaloid biosynthesis.
  Plant Physiol. 175, 120-133.

Reviews

• 1.

  Muangphrom, P., Seki, H. and Muranaka, T.
  Revealing the catalytic residues of amorpha-4,11-diene synthase (ADS): new insight for engineering terpene synthases.
  Biotarget. 2017, 1, 19.

Original Papers

• 1.

  Okano K, Hama S, Kihara M, Noda H, Tanaka T, Kondo A.
  Production of optically pure D-lactic acid from brown rice using metabolically engineered Lactobacillus plantarum.
  Appl. Microbiol. Biotechnol. 101, 1869-1875.

• 2.

  Honda K, Inoue M, Ono T, Okano K, Dekishima Y, Kawabata H.
  Improvement of operational stability of Ogataea minuta carbonyl reductase for chiral alcohol production.
  J. Biosci. Bioeng. 123, 673-678.

• 3.

  Honda K, Kimura K, Ninh PH, Taniguchi H, Okano K, Ohtake H.
  In vitro bioconversion of chitin to pyruvate with thermophilic enzymes.
  J. Biosci. Bioeng. 124, 296-301.

• 4.

  Taniguchi H, Sungwallek S, Chotchuang P, Okano K, Honda K.
  A key enzyme of the NAD+ salvage pathway in Thermus thermophilus: Characterization of nicotinamidase and the impact of its gene deletion at high temperatures.
  J. Bacteriol. 199, e00359-17.

Reviews

• 1.

  Taniguchi, H., Okano, K., Honda, K.
  Modules for in vitro metabolic engineering: Pathway assembly for bio-based production of value-added chemicals.
  Synth. Syst. Biotechnol. 2，65-74.

Original Papers

• 1.

  Kawabe,Y., Inao,T., Komatsu,S., Huang,G., Ito, A., Omasa,T., Kamihira, M.
  Improved recombinant antibody production by CHO cells using a production enhancer DNA element with repeated transgene integration at a predetermined chromosomal site.
  J. Biosci. Biotech. 123,(3), 390-397.

• 2.

  Takagi, Y., Yamazaki, T., Masuda, K., Nishii, S., Kawakami, B., Omasa, T.
  Identification of regulatory motifs in the CHO genome for stable monoclonal antibody production.
  Cytotechnology 69 (3), 451-460.

• 3.

  Takagi, Y., Kikuchi, T., Wada, R., Omasa, T.
  The enhancement of antibody concentration and achievement of high cell density CHO cell cultivation by adding nucleoside.
  Cytotechnology 69 (3), 511-521.

Original Papers

• 1.

  Pierce OM, McNair GR, He X, Kajiura H, Fujiyama K, Kermode AR.
  N-glycan structures and downstream mannose-phosphorylation of plant recombinant human alpha-L-iduronidase: toward development of enzyme replacement therapy for mucopolysaccharidosis I.
  Plant Mol Biol. 95, 593-606.

• 2.

  Ohashi H, Wahl C, Ohashi T, Elling L, Fujiyama K.
  Effective synthesis of guanosine 5'-diphospho-β-L-galactose using bacterial L-fucokinase/guanosine 5'-diphosphate-L-fucose pyrophosphorylase.
  Adv Synth Catal. 359, 4227-34.

• 3.

  Priyambada SA, Misaki R, Okamoto T, Okamoto Y, Ohashi T, Ueda K, Matsuura Y, Fujiyama K.
  Cell surface N-glycan alteration in HepAD38 cell lines expressing Hepatitis B virus.
  Virus Res. 238, 101-109.

• 4.

  Kajiura H, Suzuki N, Tokumoto Y, Yoshizawa T, Takeno S, Fujiyama K, Kaneko Y, Matsumura H, Nakazawa Y.
  Two Eucommia farnesyl diphosphate synthases exhibit distinct enzymatic properties leading to end product preferences.
  Biochimie. 139, 95-106.

• 5.

  Flores RJD, Ohashi T, Kawasaki H, Fujiyama K.
  The neutral N-linked glycans of the ustilaginomycete yeast Sympodiomycopsis paphiopedili.
  Yeast. 34, 305-317.

• 6.

  Ohashi T, Jinno J, Inoue Y, Ito S, Fujiyama K, Ishimizu T.
  A polygalacturonase localized in the Golgi apparatus in Pisum sativum.
  J Biochem. 162, 193-201.

• 7.

  Uehara Y, Tamura S, Maki Y, Yagyu K, Mizoguchi T, Tamiaki H, Imai T, Ishii T, Ohashi T, Fujiyama K, Ishimizu T.
  Biochemical characterization of rhamnosyltransferase involved in biosynthesis of pectic rhamnogalacturonan I in plant cell wall.
  Biochem Biophys Res Commun. 486, 130-136.

• 8.

  Ohashi H, Ohashi T, Kajiura H, Misaki R, Kitamura S, Fujiyama K.
  Fucosyltransferases produce N-glycans containing core L-galactose.
  Biochem Biophys Res Commun. 483, 658-63.

Original Papers

• 1.

  Suroto, D. A., Kitani, S., Miyamoto, K. T., Sakihama, Y., Arai, M., Ikeda, H., and Nihira, T.
  Activation of cryptic phthoxazolin A production in Streptomyces avermitilis by the disruption of autoregulator-receptor homologue AvaR3.
  J. Biosci. Bioeng. 124, 611-617.

• 2.

  Thao, N. B., Kitani, S., Nitta, H., Tomioka, T., and Nihira, T.
  Discovering potential Streptomyces hormone producers by using disruptants of essential biosynthetic genes as indicator strains.
  J. Antibiot. (Tokyo). 70, 1004-1008.

• 3.

  Pait, I. G. U., Kitani, S., Kurniawan, Y. N., Maeda, A., Iwai, T., Ikeda, H., and Nihira, T.
  Identification and characterization of lbpA, an indigoidine biosynthetic gene in the γ-butyrolactone signaling system of Streptomyces lavendulae FRI-5.
  J. Biosci. Bioeng. 124, 369-375.

• 4.

  Kinoshita, H., Wongsuntornpoj, S., Ihara, F., and Nihira, T.
  Anti-Rhodotorula activity of mycophenolic acid enhanced in the presence of polyene antibiotic nystatin.
  Lett. Appl. Microbiol. 64, 144-149.

Original Papers

• 1.

  Toba S, Jin M, Yamada M, Kumamoto K, Matsumoto S, Yasunaga T, Fukunaga Y, Miyazawa A, Fujita S, Itoh K, Fushiki S, Hiroaki K, Wanibuchi H, Arai Y, Nagai T, and Hirotsune S.
  Alpha-synuclein facilitates to form short unconventional microtubules that have a unique function in the axonal transport.
  Sci. Rep., 7, 16386

• 2.

  Nozaki T, Imai R, Tanbo M, Nagashima R, Tamura S, Tani T, Joti Y, Tomita M, Hibino K, Kanemaki MT, Wendt KS, Okada Y, Nagai T, and Maeshima K.
  Dynamic organization of chromatin domains revealed by superresolution live-cell imaging.
  Molecular Cell, 67(2), 282-293

• 3.

  Aoyama M, Yoshioka Y, Arai Y, Hirai H, Ishimoto R, Nagano K, Higashisaka K, Nagai T, Tsutsumi Y.
  Intracellular trafficking of particles inside endosomal vesicles is regulated by particle size.
  Journal of Controlled Release, 260, 183-193

• 4.

  Seiriki K, Kasai A, Hashimoto T, Schulze W, Niu M, Yamaguchi S, Nakazawa T, Inoue K, Uezono S, Takada M, Naka Y, Igarashi H, Tanuma M, Waschek JA, Ago Y, Tanaka KF, Hayata-Takano A, Nagayasu K, Shintani N, Hashimoto R, Kunii Y, Hino M, Matsumoto J, Yabe H, Nagai T, Fujita K, Matsuda T, Takuma K, Baba A, and Hashimoto H.
  High-speed and scalable whole-brain imaging in rodents and primates.
  Neuron, 94(6), 1085-1100

• 5.

  Matsushita J, Inagaki S, Nishie T, Sakasai T, Tanaka J, Watanabe C, Mizutani K, Miwa Y, Matsumoto K, Takara K, Naito H, Kidoya H, Takakura N, Nagai T, Takahashi S and Ema M.
  Fluorescence and bioluminescence imaging of angiogenesis in Flk1-Nano-lantern transgenic mice.
  Sci. Rep., 7, 46597

• 6.

  Chang YF, Broyles CN, Brook F, Davies MJ, Turtle C, Nagai T and Daniels MJ.
  Non-invasive phenotyping and drug testing in single cardiomyocytes or beta-cells by calcium imaging and optogenetics.
  PLoS ONE, 12(4)

• 7.

  Nakano M, Arai Y, Kotera I, Okabe K, Kamei Y and Nagai T.
  Genetically encoded ratiometric fluorescent thermometer with wide range and rapid response.
  PLoS ONE, 12(2)

• 8.

  Suzuki M, Sato M, Koyama H, Hara Y, Hayashi K, Yasue N, Imamura H, Fujimori T, Nagai T, E. Campbell R, and Ueno N.
  Distinct intracellular Ca2+ dynamics regulate apical constriction and differentially contribute to neural tube closure.
  Development, 144, 1307-1316

• 9.

  Inagaki S, Tsutsui H, Suzuki K, Agetsuma M, Arai Y, Jinno Y, Bai G,J. Daniels M, Okamura Y, Matsuda T, and Nagai T.
  Genetically encoded bioluminescent voltage indicator for multi-purpose use in wide range of bioimaging.
  Scientific Reports, 7, 42398

• 10.

  Takemoto K, Iwanari H, Tada H, Suyama K, Sano A, Nagai T, Hamakubo T, and Takahashi T.
  Optical inactivation of synaptic AMPA receptors erases fear memory.
  Nature Biotechnology, 35, 38-47

• 11.

  Kim S, Arai Y, Tani T, Takatsuka H, Saito Y, Kawashima T, Kawakami S, Miyawaki A, and Nagai T.
  Simultaneous imaging of multiple cellular events using high-accuracy fluorescence polarization microscopy.
  Microscopy, 66(2), 110-119

Reviews

• 1.

  Suzuki K and Nagai T.
  Recent progress in expanding the chemiluminescent toolbox for bioimaging.
  Current Opinion in Biotechnology, 48, 135-141

• 2.

  Nakano M, Nagai T
  Thermometers for monitoring cellular temperature.
  Journal of Photochemistry and Photobiology, C: Photochemistry Reviews, 30, 2-9

• 3.

  Agetsuma M, Matsuda T, and Nagai T
  Methods for monitoring signaling molecules in cellular compartments.
  Cell Calcium, 64, 12-19

Original Papers

• 1.

  Yoshikawa K, Toya Y, Shimizu H.
  Metabolic engineering of Synechocystis sp. PCC 6803 for enhanced ethanol production based on flux balance analysis.
  Bioprocess Biosyst. Eng. 40, 791-796.

• 2.

  Matsuda F, Kinoshita S, Nishino S, Tomita A, Shimizu H.
  Targeted proteome analysis of single-gene deletion strains of Saccharomyces cerevisiae lacking enzyme in the central carbon metabolism.
  PLoS One. 12, e0172742.

• 3.

  Matsuda F, Tomita A, Shimizu H.
  Prediction of hopeless peptides unlikely to be selected for targeted proteome analysis.
  Mass Spectrom. 6, A0056.

• 4.

  Masuda A, Toya Y, Shimizu H.
  Metabolic impact of nutrient starvation in mevalonate-producing Escherichia coli.
  Bioresour. Technol. 245, 1634-1640.

• 5.

  Kitajima S, Yoshida A, Kohno S, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Muranaka H, Wan Y, Thai TC, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen ME, Barbie DA, Hirose O, Tanaka T, Takahashi C.
  The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.
  Oncogene. 36, 5145-5157.

• 6.

  Morita K, Nomura Y, Ishii J, Matsuda F, Kondo A, Shimizu H.
  Heterologous expression of bacterial phosphoenol pyruvate carboxylase and Entner-Doudoroff pathway in Saccharomyces cerevisiae for improvement of isobutanol production.
  J. Biosci. Bioeng. 124, 263-270.

• 7.

  Okahashi N, Matsuda F, Yoshikawa K, Shirai T, Matsumoto Y, Wada M, Shimizu H.
  Metabolic engineering of isopropyl alcohol-producing Escherichia coli strains with 13C-metabolic flux analysis.
  Biotechnol. Bioeng. 114, 2782-2793.

• 8.

  Horinouchi T, Suzuki S, Kotani H, Tanabe K, Sakata N, Shimizu H, Furusawa C.
  Prediction of Cross-resistance and Collateral Sensitivity by Gene Expression profiles and Genomic Mutations.
  Sci. Rep. 7, 14009.

• 9.

  Matsusako T, Toya Y, Yoshikawa K, Shimizu H.
  Identification of alcohol stress tolerance genes of Synechocystis sp. PCC 6803 using adaptive laboratory evolution.
  Biotechnol. Biofuels. 10, 307.

Reviews

• 1.

  Matsuda F, Toya Y, Shimizu H.
  Learning from quantitative data to understand central carbon metabolism.
  Biotechnol. Adv. 35, 971-980.

Original Papers

• 1.

  Tsuji, S., Ichihashi, N.
  Translation activity of chimeric ribosomes composed of Escherichia coli and Bacillus subtilis or Geobacillus stearothermophilus subunits
  Biochem Biophys Rep, 10, 325-328 (2017)

• 2.

  Yumura, M., Yamamoto, N., Yokoyama, K., Mori, H., Yomo, T., Ichihashi, N.
  Combinatorial selection for replicable RNA by Qβ replicase while maintaining encoded gene function
  Plos ONE, 12(3): e0174130 (2017)