Original Papers

• 1.

  Shimma S, Kumada HO, Taniguchi H, Konno A, Yao I, Furuta K, Matsuda T, Ito S.
  (2016) Microscopic visualization of testosterone in mouse testis by use of imaging mass spectrometry.
  Anal. Bioanal. Chem. 408, 7607-7615.

• 2.

  Moriyama, T., Tanaka, S., Nakayama, Y., Fukumoto, M., Tsujimura, K., Yamada, K., Bamba, T., Yoneda, Y. and Fukusaki, E., Oka, M.
  (2016) Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network.
  Sci Rep. 6, 34648.

• 3.

  Kuboniwa, M., Sakanaka, A., Hashino, E., Bamba, T., Fukusaki, E. and Amano, A.
  (2016) Prediction of Periodontal Inflammation via Metabolic Profiling of Saliva.
  J Dent Res. 95, 1381-1386.

• 4.

  Mitsunaga, H., Meissner, L., Büchs, J. and Fukusaki, E.
  (2016) Branched chain amino acids maintain the molecular weight of poly(γ-glutamic acid) of Bacillus licheniformis ATCC 9945 during the fermentation.
  J Biosci Bioeng. 122, 400-5.

• 5.

  Chun, S., Bamba, T., Suyama, T., Ishijima, T., Fukusak,i E., Abe, K. and Nakai, Y.
  (2016) A High Phosphorus Diet Affects Lipid Metabolism in Rat Liver: A DNA Microarray Analysis.
  PLoS One. 11.

• 6.

  Sano, T., Iwahashi, M., Imagi, J., Sato, T., Yamashita, T., Fukusaki, E. and Bamba T.
  (2016) Relationship between 3-Methyl-2,4-nonanedione Concentration and Intensity of Light-induced Off-odor in Soy Bean Oil.
  J Oleo Sci. 65, 447-50.

• 7.

  Nakano, Y., Yamashita, T., Okuno, M., Fukusaki, E. and Bamba, T.
  (2016) In vitro steroid profiling system for the evaluation of endocrine disruptors.
  J Biosci Bioeng. 2016 122, 370-7.

• 8.

  Teoh, S. T., Kitamura, M., Nakayama, Y., Putri, S., Mukai, Y. and Fukusaki, E.
  (2016) Random Sample Consensus combined with Partial Least Squares regression (RANSAC-PLS) for microbial metabolomics data mining and phenotype improvement.
  J Biosci Bioeng. 122, 168-75.

• 9.

  Hori, K., Hori-Koriyama, N., Tsumura, K., Fukusaki, E. and Bamba, T.
  (2016) Insights into the formation mechanism of chloropropanol fatty acid esters under laboratory-scale deodorization conditions.
  J Biosci Bioeng. 122, 246-51.

• 10.

  Mitsunaga, H., Meissner, L., Palmen, T., Bamba, T., Büchs, J. and Fukusaki, E.
  (2016) Metabolome analysis reveals the effect of carbon catabolite control on the poly(γ-glutamic acid) biosynthesis of Bacillus licheniformis ATCC 9945.
  J Biosci Bioeng. 121, 413-9.

• 11.

  Jumhawan, U., Putri. S. P., Yusianto, Bamba, T. and Fukusaki, E.
  (2016) Quantification of coffee blends for authentication of Asian palm civet coffee (Kopi Luwak) via metabolomics: A proof of concept.
  J Biosci Bioeng. 122, 79-84.

• 12.

  Ohta, E., Nakayama, Y., Mukai, Y., Bamba, T. and Fukusaki, E.
  (2016) Metabolomic approach for improving ethanol stress tolerance in Saccharomyces cerevisiae.
  J Biosci Bioeng. 121, 399-405

• 13.

  Konya, Y., Bamba, T. and Fukusaki E.
  (2016) Extra-facile chiral separation of amino acid enantiomers by LC-TOFMS analysis.
  J Biosci Bioeng. 121, 349-53.

• 14.

  Noguchi, S., Putri, S. P., Lan, E. I., Laviña, W. A., Dempo, Y., Bamba, T., Liao, J. C. and Fukusaki, E.
  (2016). Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production.
  Metabolomics. 12, 26.

Original Papers

• 1.

  Sonoi, R., Kim, M.-H. and Kino-oka, M.
  (2016) Facilitation of uniform maturation of human retinal pigment epithelial cells through collective movement in culture.
  J. Biosci. Bioeng. 121, 220-226.

• 2.

  Kagawa, Y. and Kino-oka, M.
  (2016) An in silico prediction tool for the expansion culture of human skeletal muscle myoblasts.
  R. Soc. Open Sci. 3：160500.

• 3.

  Ogawa, Y., Kim, M.-H. and Kino-oka, M.
  (2016) Migration-driven aggregate behaviors of human mesenchymal stem cells on a dendrimer-immobilized surface direct differentiation toward a cardiomyogenic fate commitment.
  J. Biosci. Bioeng. 122, 627-632.

• 4.

  Mizutani, M., Samejima, H., Terunuma, H. and Kino-oka, M.
  (2016) Experience of contamination during autologous cell manufacturing in cell processing facility under the Japanese Medical Practitioners Act and the Medical Care Act.
  Regenerative Therapy 5, 25-30.

Original Papers

• 1.

  Sugiyama, M., Yagi, H.,Ishii, K., Porcar, L., Martel, A, Oyama, K., Noda, M., Yunoki, Y., Murakami, R., Inoue, R., Sato, N., Oba, Y., Terauchi, K., Uchiyama, S., and Kato, K.
  (2016) Structural characterization of the circadian clock protein complex composed of KaiB and KaiC by inverse contrast-matching small-angle neutron scattering.
  Sci. Rep. 6, 35567.

• 2.

  Zhang, Z., Ohto, U., Shibata, T., Krayukhina, E., Taoka, M., Yamauchi, Y., Tanji, H., Isobe, T., Uchiyama, S., Miyake, K., and Shimizu, T.
  (2016) Structural analysis reveals that Toll-like receptor 7 is a dual receptor for guanosine and single-stranded RNA. Immunity 45, 737-748.

• 3.

  Satoh, T., Toshimori, T., Noda, M., Uchiyama, S., and Kato, K.
  (2016) Crystal structure of ER glucosidase II heterodimeric complex consisting of catalytic subunit and its binding domain of regulatory subunit.
  Protein Sci. 25, 2095-2101.

• 4.

  Inoue, R., Takata, T., Fujii, F., Ishii, K., Uchiyama, S., Sato, N., Oba, Y., Wood, K., Kato, K., Fujii, N., Sugiyama, M.
  (2016) New insight into the dynamical system of αB-crystallin oligomers.
  Sci. Rep. 6, 29208.

• 5.

  Ishii, K., Noda, M., Uchiyama S.
  (2016) Mass spectrometric analysis of protein–ligand interactions.
  Biophysics and Physicobiology 13, 87-95.

• 6.

  Ohto, U., Ishida, H., Krayukhina, E., Uchiyama, S., Inoue, N.,, Shimizu, S.
  (2016) Structure of IZUMO1-JUNO reveals sperm-oocyte recognition during mammalian fertilization.
  Nature 534, 566-569.

• 7.

  Oda, M., Tanabe, Y., Noda, M., Inaba, S., Krayukhina, E., Fukada, H., Uchiyama, S.
  (2016) Structural and binding properties of laminarin revealed by analytical ultracentrifugation and calorimetric analyses.
  Carbohydrate Research 431, 33-36.

• 8.

  Nango, E., Akiyama, S., Maki-Yonekura, S., Ashikawa, Y., Kusakabe, Y., Krayukhina, E., Maruno, T., Uchiyama, S., Nuemket, N., Yonekura, K., Shimizu, M., Atsumi, N., Yasui, N., Hikima, T., Yamamoto, M., Kobayashi, Y., and Yamashita, A.
  (2016) Taste substance binding elicits conformational change of taste receptor T1r heterodimer extracellular domains.
  Sci. Rep. 6, 25745.

• 9.

  Kabe, Y., Nakane, T., Koike, I., Yamamoto, T., Sugiura, Y., Harada, E., Sugase, K., Shimamura, T., Ohmura, M., Muraoka, K., Yamamoto, A., Uchida, T., Iwata, S., Yamaguchi, Y., Krayukhina, E., Noda, M., Handa, H., Ishimori, K., Uchiyama, S., Kobayashi T., and Suematsu, M.
  (2016) Haem-dependent dimerization of PGRMC1/sigma-2 receptor facilitates cancer proliferation and chemoresistance.
  Nature Comm. 7, 11030.

• 10.

  Fukai-Toma, S. Kim, J.D., Park, K. E., Kuwabara, N., Shimizu, N., Krayukuhina, E., Uchiyama, S., Fukamizu, A., Shimizu, T.
  (2016) Novel helical assembly in arginine methyltransferase 8.
  J. Mol. Biol. 428, 1197-1208.

• 11.

  Fujikawa, A., Nagahira, A., Sugawara, H., Ishii, K., Imajo, S., Matsumoto, M., Kuboyama, K., Suzuki, R., Tanga, N., Noda, M., Uchiyama, S., Tomoo, T., Ogata, A., Masumura, M., and Noda, M.
  (2016) Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma.
  Sci. Rep. 6, 20473.

• 12.

  Thammaporna, R., Ishii, K., Yagi-Utsumi, M., Uchiyama, S., Hannongbua, S., and Kato, K.,
  (2016) Mass spectrometric characterization of HIV-1 reverse transcriptase interactions with non-nucleoside reverse transcriptase inhibitors.
  Biological and Pharmaceutical Bulletin 39, 450-454.

• 13.

  Amano, M., Fukui, K., Uchiyama, S.
  (2016) Suppression of methionine oxidation of a pharmaceutical antibody stored in a polymer-based syringe.
  J. Pharm. Sci. 105, 623-629.

Original Papers

• 1.

  Uyeda, A., Nakayama, S., Kato, Y., Watanabe, H. and Matsuura, T.
  (2016) Construction of an in Vitro Gene Screening System of the E. coli EmrE Transporter Using Liposome Display.
  Anal. Chem. 88, 12028-12035.

• 2.

  Ohta, N., Kato, Y., Watanabe, H., Mori, H. and Matsuura, T.
  (2016) In vitro membrane protein synthesis inside Sec translocon-reconstituted cell-sized liposomes.
  Sci. Rep. 6, 36466.

• 3.

  Nakanishi, T., Kato, Y., Matsuura, T. and Watanabe, H.
  (2016) TALEN-mediated knock-in via non-homologous end joining in the crustacean Daphnia magna.
  Sci. Rep. 6, 36252.

• 4.

  Mohamad Ishak, N. S., Kato, Y., Matsuura, T. and Watanabe, H.
  (2016) Sequence Conservation and Sexually Dimorphic Expression of the Ftz-F1 Gene in the Crustacean Daphnia magna.
  PLoS One. 11, e0154636.

Original Papers

• 1.

  Yasumoto, S., Fukushima, E.O., Seki, H. and Muranaka, T.
  (2016) Novel triterpene oxidizing activity of Arabidopsis thaliana CYP716A subfamily enzymes.
  FEBS Lett. 590, 533-540.

• 2.

  Tsukagoshi, Y., Suzuki, H., Seki, H., Muranaka, T., Ohyama, K. and Fujimoto, Y.
  (2016) Ajuga Δ24-sterol reductase catalyzes the direct reductive conversion of 24-methylenecholesterol to campesterol.
  J. Biol. Chem. 291, 8189-8198.

• 3.

  Tsukagoshi, Y., Ohyama, K., Seki, H., Akashi, T., Muranaka, T., Suzuki, H. and Fujimoto, Y.
  (2016) Functional characterization of CYP71D443, a cytochrome P450 catalyzing C-22 hydroxylation in the 20-hydroxyecdysone biosynthesis of Ajuga hairy roots.
  Phytochemistry 127, 23-28.

• 4.

  Muangphrom, P., Seki, H., Suzuki, M., Komori, A., Nishiwaki, M., Mikawa, R., Fukushima, E.O. and Muranaka, T.
  (2016) Functional analysis of amorpha-4,11-diene synthase (ADS) homologs from non-artemisinin-producing artemisia species: The discovery of novel koidzumiol and (+)-α-bisabolol synthases.
  Plant Cell Physiol. 57, 1678-1688.

• 5.

  Umemoto, N., Nakayasu, M., Ohyama, K., Yotsu-Yamashita, M., Mizutani, M., Seki, H., Saito, K. and Muranaka. T.
  (2016) Two cytochrome P450 monooxygenases catalyze early hydroxylation steps in the potato steroid glycoalkaloid biosynthetic pathway.
  Plant Physiol. 171, 2458-2467.

Reviews

• 1.

  Muangphrom, P., Seki, H., Fukushima, E.O. and Muranaka. T.
  (2016) Artemisinin-based antimalarial research: application of biotechnology to the production of artemisinin, its mode of action, and the mechanism of resistance of Plasmodium parasites.
  J. Nat. Med. 70, 318-334.

Original Papers

• 1.

  Cheng, M., Yoshiyasu, H., Okano. K., Ohtake, H., and Honda, K.
  (2016) Redirection of the reaction specificity of a thermophilic acetolactate synthase toward acetaldehyde formation.
  PLoS One 11, e0146146.

• 2.

  Honda, K., Hara, N., Cheng, M., Nakamura, A., Mandai, K., Okano, K., and Ohtake, H.
  (2016) In vitro metabolic engineering for the salvage synthesis of NAD. Metab. Eng. 35, 114-120.

• 3.

  Okano, K., Yamamoto, Y., Takano, H., Aketo, T., Honda, K.,and Ohtake, H.
  (2016) A simple technology for phosphorus recovery using acid-treated concrete sludge. Separ. Purif. Technol. 165, 173-178.

• 4.

  Polburee, P., Yongmanitchai, W., Honda, K., Ohashi, T., Yoshida, T., Fujiyama, K. (()) Lipid production from biodiesel-derived crude glycerol by Rhodosporidium fluviale DMKU-RK253 using temperature shift with high cell density. Biochem. Eng. J. 112, 208-218.

• 5.

  Okano, K., Miyamaru, S., Yamamoto, Y., Kunisada, M., Takano, H., Toda, M., Honda, K., and Ohtake, H.
  (2016) A mobile pilot-scale plant for in situ demonstration of phosphorus recovery from wastewater using amorphous calcium silicate hydrates. Separ. Purif. Technol. 170, 116-121.

Reviews

• 1.

  Honda, K.
  (2016) Chapter 16, Industrial applications of multistep enzyme reactions.
  G. Brahmachari, A. Demain, J.L. Adrio edn.
  Biotechnology of Microbial Enzymes, Elsevier, 433-450.

Original Papers

• 1.

  Kaboli, S., Miyamoto, T., Sunada, K., Sasano, Y., Sugiyama, M. and Harashima, S.
  (2016) Improved stress resistance and ethanol production by segmental haploidization of the diploid genome in Saccharomyces cerevisiae.
  J. Biosci. Bioeng. 121, 638-644.

• 2.

  Sugiyama, M., Akase, SP., Nakanishi, R., Kaneko, Y. and Harashima, S.
  (2016) Overexpression of ESBP6 improves lactic acid resistance and production in Saccharomyces cerevisiae.
  J. Biosci. Bioeng. 122, 415-420.

• 3.

  Sasano, Y., Nagasawa, K., Kaboli, S., Sugiyama, M. and Harashima, S.
  (2016) CRISPR-PCS: a powerful new approach to inducing multiple chromosome splitting in Saccharomyces cerevisiae.
  Sci. Rep. 17, 30278.

• 4.

  Kitichantaropas, Y., Boonchird C., Sugiyama, M., Kaneko, Y., Harashima, S., Auesukaree, C.
  (2016) Cellular mechanisms contributing to multiple stress tolerance in Saccharomyces cerevisiae strains with potential use in high-temperature ethanol fermentation.
  AMB Express. 6, 107.

Original Papers

• 1.

  Badsha, M.B., Kurata, H., Onitsuka, M., Oga, T. and Omasa, T.
  (2016) Metabolic analysis of antibody producing CHO cell culture under different stresses conditions.
  Journal of Bioscience and Bioengineering, 122, 1, 117-124.

• 2.

  Yamano, N., Takahashi, M., Ali Haghparast, S.M., Onitsuka, M., Kumamoto, T., Frank, J. and Omasa, T.
  (2016) Increased recombinant protein production owing to expanded opportunities for vector integration in high chromosome number Chinese hamster ovary cells.
  Journal of Bioscience and Bioengineering, 122, 2, 226-231.

• 3.

  Okochi, M., Kamiya, T., Omasa, T., Tanaka, T. and Honda, H.
  (2016) Rapid colorimetric antibody detection using a dual-function peptide probe for silver nanoparticle aggregation and antibody recognition.
  Analytical Sciences, 32, 1 , 93-97.

• 4.

  Uehara, R., Takano, K., Kanaya, S. and Koga, Y.
  (2016) Hyperthermophilic subtilisin-like protease from Themococcus kodakarensis. Biotechnology of Microbial Enzymes, production, biocatalysis and industrial applications,
  Academic Press, p81-117.

• 5.

  Matsuyama, R., Yamano, N., Kawamura, N. and Omasa, T.
  (2016) Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.
  Journal of Bioscience and Bioengineering, 123, 3, 382-389.

Reviews

• 1.

  Nakashima, Y. and Omasa, T.
  (2016) What kind of signaling maintains pluripotency and viability in human-induced pluripotent stem cells cultured on laminin-511 with serum-free medium?
  Bioreseach Open Access., 5, 1, 84–93.

Original Papers

• 1.

  Ohashi, T., Hasegawa, Y., Misaki, R. and Fujiyama, K.
  (2016) Substrate preference of citrus naringenin rhamnosyltransferases and their application to flavonoid glycoside production in fission yeast.
  Appl. Micobiol. Biotechnol. 100, 687-96.

• 2.

  Roongsawang, N., Puseenam, A., Kitikhun, S., Sae-Tang, K., Harnpicharnchai, P., Ohashi, T., Fujiyama, K., Tirasophon, W. and Tanapongpipat, S.
  (2016) A novel potential signal peptide sequence and overexpression of ER-resident chaperones enhance heterologous protein secretion in thermotolerant methylotrophic yeast Ogataea thermomethanolica.
  Appl. Biochem. Biotechnol. 178, 710-24.

• 3.

  Trempel, F., Kajiura, H., Ranf, S., Grimmer, J., Westphal, L., Zipfel, C., Scheel, D., Fujiyama, K. and Lee, J.
  (2016) Altered glycosylation of exported proteins, including surface immune receptors, compromises calcium and downstream signaling responses to microbe-associated molecular patterns in Arabidopsis thaliana.
  BMC Plant Biol. 16:31.

• 4.

  Limkul, J., Iizuka, S., Sato, Y., Misaki, R., Ohashi, T., Ohashi, T. and Fujiyama, K.
  (2016) The production of human glucocerebrosidase in glyco-engineered Nicotiana benthamiana plants.
  Plant Biotechnol. J. 14, 1682-94.

• 5.

  Polburee, P., Yongmanitchai, W., Honda, K., Ohashi, T., Yoshida, T., Fujiyama, K. and Limtong, S.
  (2016) Lipid production from biodiesel-derived crude glycerol by Rhodosporidium fluviale DMKU-RK253 using temperature shift with high cell density.
  Biochem. Eng. J. 112, 208-18.

• 6.

  Takamatsu, S., Shimomura, M., Kamada, Y., Maeda, H., Sobajima, T., Hikita, H., Iijima, M., Okamoto, Y., Misaki, R., Fujiyama, K., Nagamori, S., Kanai, Y., Takehara, T., Ueda, K., Kuroda, S. and Miyoshi E.
  (2016) Core-fucosylation plays a pivotal role in hepatitis B pseudo virus infection: a possible implication for HBV glycotherapy.
  Glycobiology. 26, 1180-1189.

• 7.

  Misaki, R., Fukura, N., Kajiura, H., Yasugi, M., Kubota-Koketsu, R., Sasaki, T., Momota, M., Ono, K., Ohashi, T., Ikuta, K. and Fujiyama, K.
  (2016) Recombinant production and characterization of human anti-influenza virus monoclonal antibodies identified from hybridomas fused with human lymphocytes.
  Biologicals.44, 394-402.

• 8.

  De Martinis, D., Rybicki, E.P., Fujiyama, K., Franconi, R. and Benvenuto, E.
  (2016) Editorial: Plant Molecular Farming: Fast, Scalable, Cheap, Sustainable.
  Front Plant Sci. 7, 1148.

Original Papers

• 1.

  Sultan, S. P., Kitani, S., Miyamoto, K.T., Iguchi, H., Atago, T., Ikeda, H., and Nihira, T.
  (2016) Characterization of AvaR1, a butenolide-autoregulator receptor for biosynthesis of a Streptomyces hormone in Streptomyces avermitilis.
  Appl. Microbiol. Biotechnol. 100, 9581-9591.

• 2.

  Intra, B., Euanorasetr, J., Nihira, T., and Panbangred, W.
  (2016) Characterization of a γ-butyrolactone synthetase gene homologue (stcA) involved in bafilomycin production and aerial mycelium formation in Streptomyces sp. SBI034.
  Appl. Microbiol. Biotechnol. 100, 2749-2760.

• 3.

  Kurniawan, Y.N., Kitani, S., Iida, A., Maeda, A., Nijeholt, J.L., Lee, Y.J., and Nihira, T.
  (2016) Regulation of production of the blue pigment indigoidine by the pseudo γ-butyrolactone receptor FarR2 in Streptomyces lavendulae FRI-5.
  J. Biosci. Bioeng. 121, 372-379.

• 4.

  Kinoshita, H., Yoshioka, M., Ihara, F., and Nihira, T.
  (2016) Cryptic antifungal compounds active by synergism with polyene antibiotics.
  J. Biosci. Bioeng. 121, 394-398.

Original Papers

• 1.

  Morikawa, TJ., Fujita, H., Kitamura, A., Horio, T., Yamamoto, J., Kinjo, M., Sasaki, A., Machiyama, H., Yoshizawa, K., Ichimura, T., Imada, K., Nagai, T and Watanabe, TM.
  (2016) Dependence of fluorescent protein brightness on protein concentration in solution and enhancement of it.
  Sci Rep. 6, 22342.

• 2.

  Pandey, K., Ferreira, PE., Ishikawa, T., Nagai, T., Kaneko, O. and Yahata, K.
  (2016) Ca2+ monitoring in Plasmodium falciparum using the yellow cameleon-Nano biosensor.
  Sci Rep. 6, 23454.

• 3.

  Lissek, T., Obenhaus, HA., Ditzel, DA., Nagai, T., Miyawaki, A., Sprengel, R. and Hasan, MT.
  (2016) General Anesthetic Conditions Induce Network Synchrony and Disrupt Sensory Processing in the Cortex.
  Front. Cell. Neurosci. 10, 64(1-14).

• 4.

  Ohta, Y., Kamagata, T., Mukai, A., Takada, S., Nagai, T. and Horikawa, K.
  (2016) Nontrivial Effect of the Color-Exchange of a Donor/Acceptor Pair in the Engineering of Förster Resonance Energy Transfer (FRET)-Based Indicators.
  ACS Chem Biol. 11, 1816-1822.

• 5.

  Sakamaki, K., Ishii, TM., Sakata, T., Takemoto, K., Takagi, C., Takeuchi, A., Morishita, R., Takahashi, H., Nozawa, A., Shinoda, H., Chiba, K., Sugimoto, H., Saito, A., Tamate, S., Satou, Y., Jung, SK., Matsuoka, S., Koyamada, K., Sawasaki, T., Nagai, T. and Ueno N.
  (2016) Dysregulation of a potassium channel, THIK-1, targeted by caspase-8 accelerates cell shrinkage.
  Biochim Biophys Acta. 1863, 2766-2783.

• 6.

  Lu-Walther, HW., Hou, W., Kielhorn, M., Arai, Y., Nagai, T., Kessels, MM., Qualmann, B. and Heintzmann, R.
  (2016) Nonlinear Structured Illumination Using a Fluorescent Protein Activating at the Readout Wavelength.
  PLoS One. 11, e0165148(1-14).

• 7.

  Shimada, N., Saito, M., Shukuri, S., Kuroyanagi, S., Kuboki, T., Kidoaki, S., Nagai, T. and Maruyama A.
  (2016) Reversible Monolayer/Spheroid Cell Culture Switching by UCST-Type Thermoresponsive Ureido Polymers.
  ACS Appl Mater Interfaces. 8, 31524-31529.

• 8.

  Mochida, S., Rata, S., Hino, H., Nagai, T. and Novák, B.
  (2016) Two Bistable Switches Govern M Phase Entry. Curr Biol. 26, 3361-3367.

• 9.

  Takemoto, K., Iwanari, H., Tada, H., Suyama, K., Sano, A., Nagai, T., Hamakubo, T. and Takahashi, T.
  (2016) Optical inactivation of synaptic AMPA receptors erases fear memory.
  Nat Biotechnol. 35, 38-47.

• 10.

  Suzuki, K., Kimura, T., Shinoda, H., Bai, G., Daniels, MJ., Arai, Y., Nakano, M. and Nagai T.
  (2016) Five colour variants of bright luminescent protein for real-time multicolour bioimaging.
  Nat Commun. 14, 13718(1-10).

Reviews

• 1.

  Inagaki, S and Nagai, T.
  (2016) Current progress in genetically encoded voltage indicators for neural activity recording.
  Curr Opin Chem Biol. 33, 9-5.

Original Papers

• 1.

  Matsushima, Y., Hirasawa, T. and Shimizu, H.
  (2016) Enhancement of 1,5-diaminopentane production in a recombinant strain of Corynebacterium glutamicum by Tween 40 addition.
  J. Gen. Appl. Microbiol. 62(1),42-45.

• 2.

  Hayakawa, K., Matsuda, F. and Shimizu, H.
  (2016) Metabolome analysis of Saccharomyces cerevisiae and optimization of culture medium for S-adenosyl-L-methionine production.
  AMB Express 6(1),1-8.

• 3.

  Maeda, K., Okahashi, N., Toya, Y., Matsuda, F. and Shimizu, H.
  (2016) Investigation of useful carbon tracers for 13C-metabolic flux analysis of Escherichia coli by considering five experimentally determined flux distributions.
  Metab.Eng.Comm. 3,187-195.

• 4.

  Matsuda, F.
  (2016) Regular expressions of MS/MS spectra for partial annotation of metabolite features.
  Metabolomics 12,113

• 5.

  Okahashi, N., Kawana, S., Iida, J., Shimizu, H. and Matsuda, F.
  (2016) GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to 13C -metabolic flux analysis of Escherichia coli central metabolism.
  Anal. Bioanal. Chem. 408(22), 6133-6140

• 6.

  Nugroho, R,H., Yoshikawa, K., Matsuda, F. and Shimizu, H.
  (2016) Positive effects of proline addition on the central metabolism of wild-type and lactic acid-producing Saccharomyces cerevisiae strains.
  Biopro cess Biosyst. Eng. 39(11),1711-1716.

• 7.

  Wada, K., Toya, Y., Banno, S., Yoshikawa, K., Matsuda, F. and Shimizu, H.
  (2016) 13C-metabolic flux analysis for mevalonate producing Escherichia coli.
  J. Biosci. Bioeng. 123(2),177-182.

• 8.

  Namakoshi, K., Nakajima, T., Yoshikawa, K., Toya, Y. and Shimizu, H.
  (2016) Combinatorial deletions of glgC and phaCE enhance ethanol production in Synechocystis sp. PCC 6803.
  J. Biotechnol. 239,13-19.

• 9.

  Nakajima, T., Yoshikawa, K., Toya, Y., Matsuda, F. and Shimizu, H.
  (2016) Metabolic flux analysis of Synechocystis sp. PCC6803 ΔnrtABCD mutant reveals a mechanism for metabolic adaptation to nitrogen-limited conditions.
  Plant Cell Physiol. 58(3), 537-545.

Reviews

• 1.

  Matsuda, F.
  (2016) Technical challenges in mass spectrometry-based metabolomics.
  Mass Spectrometry, 5.

• 2.

  Hirasawa, T. and Shimizu, H.
  (2016) Recent advances in amino acid production by microbial cells.
  Curr. Opin. Biotechnol. 42, 133-146.

Original Papers

• 1.

  Bansho, Y., Furubayashi, T., Ichihashi, N.* and Yomo, T.* (*co-corresponding)
  (2016) Host-parasite oscillation dynamics and evolution in a compartmentalized RNA replication system.
  Proc. Nat. Aca. Sci. USA, 113, 4045-4050.

• 2.

  Mizuuchi, R., Ichihashi, N.* and Yomo, T. (*corresponding)
  (2016) Adaptation and diversification of an RNA replication system under initiation- or termination-impaired translational conditions.
  ChemBioChem, 17, 1229-1232.

• 3.

  Sunami, T., Ichihashi, N., Nishikawa, T., Kazuta, Y. and Yomo, T.
  (2016) Effect of Liposome Size on Internal RNA Replication Coupled with Replicase Translation.
  ChemBioChem, 17, 1282-1289.

• 4.

  Aita, T., Ichihashi, N. and Yomo, T.
  (2016) Inference of fitness values and putative appearance time points for evolvable self-replicating molecules from time series of occurrence frequencies in an evolution reactor.
  J. Theoretical Biol., 401, 38-42.

Reviews

• 1.

  Ichihashi, N. and Yomo, T.
  (2016) Constructive approaches for understanding the origin of self-replication and evolution.
  Life, 6, 26-37.