Publication list

2023

1. Junya Kamioka, Kei Sasaki, Koichi Baba, Tomoyo Tanaka,　Yosuke Teranishi, Takahiro Ogasawara, Masukazu Inoie, Ken-ichiro Hata, Kohji Nishida, and Masahiro Kino-oka: “Agent-Based Approach for Elucidating the Release from Collective Arrest of Cell Motion in Corneal Epithelial Cell Sheet", J. Biosci. Bioeng. Vol. 136 No. 6, pp. 477-486 (2023). (doi: 10.1016/j.jbiosc.2023.10.003)

2. Junya Kamioka, Kei Sasaki, Koichi Baba, Tomoyo Tanaka, Yosuke Teranishi, Takahiro Ogasawara, Masukazu Inoie, Ken-ichiro Hata, Kohji Nishida, and Masahiro Kino-oka: "Agent-Based Approach for Elucidating the Release from Collective Arrest of Cell Motion in Corneal Epithelial Cell Sheet", J. Biosci. Bioeng. in press

3. Akihiro Hashida, Taro Nakazato, Toshimasa Uemura, Li Liu, Shigeru Miyagawa, Yoshiki Sawa, and Masahiro Kino-oka: “Effect of Morphological Change on the Maturation of Human Induced Pluripotent Stem Cell-Derived Cardiac Tissue in Rotating Flow Culture”, Regen. Ther. Vol. 24, 479-488 (2023).（doi: 10.1016/j.reth.2023.09.002）

4. Mee-Hae Kim, Masaki Kuroda, Ding Ke, Naruchit Thanuthanakhun, and Masahiro Kino-oka : “An in vitro Culture Platform for Studying the Effect of Collective Cell Migration on Spatial Self-organization within Induced Pluripotent Stem Cell Colonies”, J. Biol. Eng., Vol. 17, No. 25 (2023).(doi: 10.1186/s13036-023-00341-z)

5. Isuru A. Udugma, Sara Badr, Keita Hirono, Benedikt Scholz, Yusuke Hayashi, Masahiro Kino-oka, and Hirokazu Sugiyama:“The Role of Process Systems Engineering in Applying Quality by Design (QbD) in Mesenchymal Stem Cell Production”, Comput. Chem. Eng., Vol. 172, 108144 (2023).(doi:10.1016/j.compchemeng.2023.108144).

6. Benedikt X. Scholz, Yusuke Hayashi, Isuru A. Udugama, Masahiro Kino-oka, and Hirokazu Sugiyama:“A CFD Model-Based Design of Seeding Processes for Two-Dimensional Mesenchymal Stem Cell Cultivation”, Comput. Chem. Eng., Vol.171, 108157 (2023).(doi:10.1016/j.compchemeng.2023.108157)

7. Parichut Thummarati, Wanida Laiwattanapaisal, Rikiya Nitta, Megumi Fukuda, Artchaya Hassametto, and Masahiro Kino-oka, “Recent Advances in Cell Sheet Engineering: from Fabrication to Clinical Translation”, Bioengineering, Vol.10, 211 (2023). (doi:10.3390/bioengineering10020211)

8. Mee-Hae Kim, Naruchit Thanuthanakhun, and Masahiro Kino-oka: “Novel Strategy to Improve Hepatocyte Differentiation Stability through Synchronized Behavior-Driven Mechanical Memory of iPSCs”, Biotechnol. Bioeng., Vol.120, No.2, pp.593-607 (2023). (doi: 10.1002/bit.28285)

2022

9. Atsunori Tsuchiya, Shuji Terai, Ikki Horiguchi, Yasuhiro Homma, Atsuhiro Saito, Norimasa Nakamura, Yoji Sato, Takahiro Ochiya, Masahiro Kino-oka ; Working Group of Attitudes for Preparation and Treatment of Exosomes of Japanese Society of Regenerative MedicineBasic points to consider regarding the preparation of extracellular vesicles and their clinical applications in Japan: “Basic Points to Consider Regarding the Preparation of Extracellular Vesicles and Their Clinical Applications in Japan”, Regen.Ther., Vol.21, pp.19-24 (2022). (doi: 10.1016/j.reth.2022.05.003)Naruchit Thanuthanakhun, Mee-Hae Kim, and Masahiro Kino-oka: “Cell Behavioral Dynamics as a Cue in Optimizing Culture Stabilization in Bioprocessing of Pluripotent Stem Cells”, Bioengineering, Vol.9, No.11, p.669 (2022). (doi: 10.3390/bioengineering9110669)

10. Naruchit Thanuthanakhun, Mee-Hae Kim, and Masahiro Kino-oka: “Cell Behavioral Dynamics as a Cue in Optimizing Culture Stabilization in Bioprocessing of Pluripotent Stem Cells”, Bioengineering, Vol.9, No.11, p.669 (2022). (doi: 10.3390/bioengineering9110669)

11. Takaki Matsumoto, Mee-Hae Kim, and Masahiro Kino-oka: “Effect of Rho-Associated Kinase Inhibitor on Growth Behaviors of Human Induced Pluripotent Stem Cells in Suspension Culture”, Bioengineering, Vol.9, No.11, pp.613 (2022). (doi:10.3390/bioengineering9110613)

12. Morikuni Tobita, Yosuke Masubuchi, Yorimasa Ogata, Akio Mitani, Takeshi Kikuchi, TakuToriumi, Jorge Luis Montenegro Raudales, Hiroshi Mizuno, Yuki Suzuki, Keiko Wakana, Hikari Yoneda, Reika Kamijo, Masahiro Kino-oka, Tomohiro Morio, Kiyoshi Okada, Shinya Murakami, Masaki Honda: “Study Protocol for Periodontal Tissue Regeneration with a Mixture of Autologous Adipose-Derived Stem Cells and Platelet Rich Plasma: A Multicenter, Randomized, Open-Label Clinical Trial”, Regen. Ther., Vol. 21, pp. 436-441 (2022). (doi:10.1016/j.reth.2022.09.008)

13. Adithya Nair, Ikki Horiguchi, Kazuhiro Fukumori, and Masahiro Kino-oka: “Development of Instability Analysis for the Filling Process of Human-Induced Pluripotent Stem Cell Products”, Biochem. Eng. J., Vol. 185, 108506 (2022). (doi:10.1016/j.bej.2022.108506)

14. Benedikt X. Scholz, Yusuke Hayashi, Isuru A. Udugama, Masahiro Kino-oka, and Hirokazu Sugiyama: “A Multilayered Approach to Scale-Up Forced Convection-Based Freezing of Human induced Pluripotent Stem Cells”, Comput. Chem. Eng., Vol. 163, 107851 (2022). (doi:10.1016/j.compchemeng.2022.107851)

15. Manabu Mizutani, Kentaro Nakajima, and Masahiro Kino-oka: “Approach of Resource Expenditure Estimation Toward Mechanization in the Manufacturing of Cell-Based Products”, Regen. Ther., Vol. 20, pp. 9-17 (2022). (doi.org/10.1016/j.reth.2022.02.004)

16. Keita Hirono, Isuru Udugama, Yusuke Hayashi, Masahiro Kino-oka, and Hirokazu Sugiyama: “A Dynamic and Probabilistic Design Space Determination Method for Mesenchymal Stem Cell Cultivation Processes”, Ind. Eng. Chem. Res., Vol. 61, 7009-7019 (2022). (doi:10.1021/acs.iecr.2c00374)

17. Yusuke Hayashi, Masahiro Kino-oka, and Hirokazu Sugiyama: “Hybrid-Model-Based Design of Fill-Freeze-Thaw Processes for Human Induced Pluripotent Stem Cells Considering Productivity and Quality”, Comput. Chem. Eng., Vol. 156, 107566 (2022). (doi:10.1016/j.compchemeng.2021.107566)

2021

18. Mee-Hae Kim and Masahiro Kino-oka: “Mechanobiological Conceptual Framework for Assessing Stem Cell Bioprocess Effectiveness”, Biotechnol. Bioeng., Vol. 118, No. 2, pp. 4537-4549 (2021). (doi.org/10.1002/bit.27929)

19. Mee-Hae Kim, Fitria Dwi Ayuningtyas, and Masahiro Kino-oka: “Novel Approach to Enhance Aggregate Migration-Driven Epigenetic Memory Which Induces Cardiomyogenic Differentiation on a Dendrimer-Immobilized Surface”, J. Biosci. Bioeng., Vol. 132, No. 4, pp. 390-398 (2021). (doi.org/10.1016/j.jbiosc.2021.06.009)

20. Liya Wang, Ryosuke Isobe, Yasunori Okano, Masahiro Kino-oka, Hiroyuki Matsuda, and Tomohiro Tokura: “Bayesian Optimization for Hydrodynamic Characterization of a Cylindrical Orbitally Shaken Bioreactor with a Bump at the Bottom”, J. Chem. Eng. Japan, Vol. 54, No. 9 pp. 493-499 (2021). (doi:10.1252/jcej.21we047)

21. Riku Yamamoto and Masahiro Kino-oka: “Design of Suspension Culture System with Bubble Sparging for Human Induced Pluripotent Stem Cells in a Plastic Fluid”, J. Biosci. Bioeng., Vol. 132, No. 2, pp. 190-197 (2021). (doi:10.1016/j.jbiosc..2021.04.010)

22. Mee-Hae Kim, Naruchit Thanuthanakhun, Shun Fujimoto, and Masahiro Kino-oka: “The Impact of Initial Seeding Density on Behavioral Epigenetic Memory Contributing to Pluripotent state of iPS cells”, Stem Cell Res. Vol. 236, No. 7, pp. 4895-4996 (2021). (doi:10.1002/jcp.30211)

23. Liya Wang, Ryosuke Isobe, Yasunori Okano, and Masahiro Kino-oka: “Numerical Investigation on Suspension Culture in an Orbitally Shaken Cylindrical Bioreactor”, J. Chem. Eng. Japan, Vol. 54, No. 7, pp. 351-357 (2021). (doi:10.1252/jcej.21we015)

24. Naruchit Thanuthanakhun, Masahiro Kino-oka, Suparerk Borwornpinyo, Yuzuru Ito, and Mee-Hae Kim: “The Impact of Culture Dimensionality on Behavioral Epigenetic Memory Contributing to Pluripotent State of iPS Cells”, Journal of Cellular Physiology, Vol. 236, No. 7, pp. 4985–4996 (2021). (doi:10.1002/jcp.30211)

25. Parichut Thummarati and Masahiro Kino-oka: “Exogenous FGF-2 prolongs endothelial connection in multilayered human skeletal muscle cell sheet”, J. Biosci. Bioeng., Vol. 131, No. 6, pp. 686-695 (2021).

26. Liya Wang, Ryosuke Isobe, Yoshiki Kanemaru, Yasunori Okano, and Masahiro Kino-oka: “Numerical Optimization of Particle Dispersion in Wave Bioreactor for Static Cell Cultivation”, J. Chem. Eng. Japan, Vol. 54, No. 3, pp. 87-92 (2021). (doi:10.1252/jcej.20we226)

27. Thi Nhu Trang Nguyen, Kei Sasaki, and Masahiro Kino-oka: “Development of a Kinetic Model Expressing Anomalous Phenomena in Human Induced Pluripotent Stem Cell Culture”, J. Biosci. Bioeng., Vol. 131, No. 3, pp. 305-313 (2021). (doi:10.1016/j.jbiosc.2020.10.013)

28. Ikki Horiguchi and Masahiro Kino-oka: “Current Developments in the Stable Production of Human Induced Pluripotent Stem Cells”, Engineering, Vol. 7, No. 2, pp. 144-152 (2021). (doi:10.1016/j.eng.2021.01.001)

29. Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, and Hirokazu Sugiyama: “Model-Based Assessment of Temperature Profiles in Slow Freezing for Human Induced Pluripotent Stem Cells”, Comput. Chem. Eng., Vol. 144, 107150 (2021). (doi:10.1016/j.compchemeng.2020.107150)

2020

30. Parichut Thummarati and Masahiro Kino-oka: “Effect of Co-culturing Fibroblasts in Human Skeletal Muscle Cell Sheet on Angiogenic Cytokine Balance and Angiogenesis”, Front. Bioeng. Biotechnol., Vol. 8，578140 (2020). (doi:10.3389/fbioe.2020.578140)

31. Hirokazu Sugiyama, Masaki Shiokaramatsu, Masashi Kagihiro, Kazuhiro Fukumori, Ikki Horiguchi, and Masahiro Kino-oka: “Apoptosis-Based Method for Determining Lot Sizes in the Filling of Human-Induced Pluripotent Stem Cells”, J. Tissue Eng. Regen. Med., Vol. 14, No. 11, pp. 1641-1651 (2020). (doi:10.1002/term.3127)

32. Fitria Dwi Ayuningtyas, Mee-Hae Kim, Masahiro Kino-oka: “Muscle Lineage Switching by Migratory Behaviour-Driven Epigenetic Modifications of Human Mesenchymal Stem Cells on a Dendrimer-Immobilized Surface”, Acta Biomater., Vol. 106, pp. 170-180 (2020). (doi:10.1016/j.actbio.2020.02.026)

33. Akihiro Hashida, Toshimasa Uemura, and Masahiro Kino-oka: “Kinetics on Aggregate Behaviors of Human Induced Pluripotent Stem Cells in Static Suspension and Rotating Flow Cultures”, J. Biosci. Bioeng. Vol. 129, No. 4, pp. 494-501 (2020). (doi:10.1016/j.jbiosc.2019.11.005)

34. Masashi Kagihiro, Kazuhiro Fukumori, Ikki Horiguchi, Mee-Hae Kim, and Masahiro Kino-oka: “Suppression of Time-Dependent Decay by Controlling the Redox Balance of Human Induced Pluripotent Stem Cells Suspended in a Cryopreservation Solution”, Biochem. Eng. J., Vol. 155, 107465 (2020). (doi:10.1016/j.bej.2019.107465)

35. Mee-Hae Kim and Masahiro Kino-oka: “Designing a Blueprint for Next-Generation Stem Cell Bioprocessing Development”, Biotechnol. Bioeng., Vol. 117, No. 3, pp. 832-843 (2020). (doi.org/10.1002/bit.27228)

36. Koichi Baba, Kei Sasaki, Mio Morita, Tomoyo Tanaka, Yosuke Teranishi, Takahiro Ogasawara, Yoshinori Oie, Izumi Kusumi, Masukazu Inoie, Kenichiro Hata, Andrew Quantock, Masahiro Kino-oka, and Kohji Nishida: “Cell Jamming, Stratification and p63 Expression in Cultivated Human Corneal Epithelial Cell Sheets”, Sci. Rep, Vol. 10, N0.9282(2020). (doi.org/10.1038/s41598-020-64394-6)

37. Mee-Hae Kim and Masahiro Kino-oka: “Bioengineering Considerations for a Nurturing Way to Enhance Scalable Expansion of Human Pluripotent Stem Cells”, Biotechnol. J., Vol. 15, No. 4, 1900314 (2020). (doi:10.1002/biot.201900314)

38. Yusuke Hayashi, Ikki Horiguchi, Masahiro Kino-oka, and Hirokazu Sugiyama: “Slow Freezing Process Design for Human Induced Pluripotent Stem Cells by Modeling Intracontainer Variation”, Computers and Chemical Engineering,　Vol. 132, 106597 (2019). (https://doi.org/10.1016/j.compchemeng.2019.106597)

2019

39. Chaiyong Koaykul, Mee-Hae Kim, Yumi Kawahara, Louis Yuge, and Masahiro Kino-oka: “Maintenance of Neurogenic Differentiation Potential in Passaged Bone Marrow-Derived Human Mesenchymal Stem Cells Under Simulated Microgravity Conditions”, Stem Cells and Development, Vol. 28, No. 23, pp. 1552–1561 (2019). (doi:10.1089/ scd.2019.0146)

40. Yuma Kato, Takuya Matsumoto, and Masahiro Kino-oka; “Effect of Liquid Flow by Pipetting during Medium Change on Deformation of hiPSC Aggregates”, Regen. Ther., Vol. 12, pp. 20-26 (2019). (doi:10.1016/j.reth.2019.03.004)

41. Yuuki Ogawa, Manabu Mizutani, Ryuta Okamoto, Hideki Kitajima, Sachiko Ezoe, and Masahiro Kino-oka: “Understanding the Formation and Behaviors of Droplets toward Consideration of Changeover during Cell Manufacturing”, Regen. Ther., Vol. 12, pp. 36-42 (2019). (doi:10.1016/j.reth.2019.04.002)

42. Atsushi Sekimoto, Yoshiki Kanemaru, Yasunori Okano, Kei Kanie, Ryuji Kato, and Masahiro Kino-oka: “Numerical Investigation of Particle Dispersion in the Preprocessing Stage for a Static Cell Cultivation”, Regen. Ther., Vol. 12, pp. 83-87 (2019). (doi:10.1016/j.reth.2019.04.003)

43. Vytautas Galvanauskas, Rimvydas Simutis, Suman Chandra Nath, and Masahiro Kino-oka: “Kinetic Modeling of Human Induced Pluripotent Stem Cell Expansion in Suspension Culture”, Regen. Ther., Vol. 12, pp. 88-93 (2019) (doi:10.1016/j.reth.2019.04.007)

44. Hirokazu Suigyama, Masaki Shiokaramatsu, and Masahiro Kino-oka: “A Distribution-Based Approach for Determining Lot Sizes in The Filling of Human-Induced Pluripotent Stem Cells”, Regen. Ther., Vol. 12, pp. 94-101 (2019). ( doi:10.1016/j.reth.2019.04.012)

45. Manabu Mizutani, Hiroshi Terunuma, Hazuki Samejima, Keisuke Ashiba, and Masahiro Kino-oka: “Variation in The Manufacturing Reproducibility of Autologous Cell-Based Products Depending on Raw Material Shipment Conditions”, Regen. Ther., Vol. 12, pp. 102-107 (2019). (doi:10.1016/j.reth.2019.04.012)

46. Chaiyong Koaykul, Mee-Hae Kim, Yumi Kawahara, Louis Yuge, and Masahiro Kino-oka: “Alterations in Nuclear Lamina and the Cytoskeleton of Bone Marrow-derived Human Mesenchymal Stem Cells Cultured Under Simulated Microgravity Conditions”, Stem Cells and Development, Vol. 28, No. 17 (2019). (doi:10.1089/scd.2018.0229)

47. Masahiro Kino-oka, Manabu Mizutani, and Nicholas Medcalf: “Cell manufacturability”, Cell & Gene Therapy Insights, Vol. 5, No. 10, pp. 1347-1359 (2019). (doi:10.18609/cgti.2019.140)

48. Hirokazu Suigyama, Masaki Shiokaramatsu, and Masahiro Kino-oka: “A Distribution-Based Approach for Determining Lot Sizes in The Filling of Human-Induced Pluripotent Stem Cells”, Regenerative Therapy, in press. (https://doi.org/10.1016/j.reth.2019.04.012)

49. Manabu Mizutani, Hiroshi Terunuma, Hazuki Samejima, Keisuke Ashiba, and Masahiro Kino-oka: “Variation in The Manufacturing Reproducibility of Autologous Cell-Based Products Depending on Raw Material Shipment Conditions”, Regenerative Therapy, in press. (https://doi.org/10.1016/j.reth.2019.04.012)

50. Thi Nhu Trang Nguyen, Kei Sasaki, and Masahiro Kino-oka: “Elucidation of Human Induced Pluripotent Stem Cell Behaviors in Colonies Based on a Kinetic Model”, J. Biosci. Bioeng., Vol. 127, No. 5, pp. 625-632(2019). (doi:10.1016/j.jbiosc.2018.10.016)

51. Eri Shuzui, Mee-Hae Kim, Keisuke Azuma, Yukako Fujinaga, and Masahiro Kino-oka: “Maintenance of an Undifferentiated State of Human-Induced Pluripotent Stem Cells through Botulinum Hemagglutinin-Mediated Regulation of Cell Behavior”, J. Biosci. Bioeng., in press. (doi:10.1016/j.jbiosc.2018.11.014)

52. Eri Shuzui, Mee-Hae Kim, and Masahiro Kino-oka: “Anomalous cell migration triggers a switch to deviation from the undifferentiated state in colonies of human induced pluripotent stems on feeder layers”, J. Biosci. Bioeng., Vol. 127, No. 2, pp. 246-255 (2019). (doi.org/10.1016/j.jbiosc.2018.07.020)

53. Mee-Hae Kim, Kazuhiro Takeuchi, and Masahiro Kino-oka: “Role of cell-secreted extracellular matrix formation in aggregate formation and stability of human induced pluripotent stem cells in suspension culture”, Biosci. Bioeng., Vol. 127, No. 3, pp. 372-380 (2019). (doi:10.1016/j.jbiosc.2018.08.010)

54. Jessica Chang, Mee-Hae Kim, Eviryanti Agung, Sho Senda, and Masahiro Kino-oka: “Effect of migratory behaviors on human induced pluripotent stem cell colony formation on different extracellular matrix proteins”, Regenerative Therapy, Vol. 10, pp. 27-35 (2019). (doi.org/10.1016/j.reth.2018.10.004)

2018

55. Riri Chihara, Hideki Kitajima, Yuuki Ogawa, Hiroaki Nakamura, Shozo Tsutsui, Manabu Mizutani, Masahiro Kino-oka and Sachiko Ezoe: “Effects of Residual H₂O₂ on the Growth of MSCs after Decontamination”, Regenerative Therapy, Vol. 9, pp. 111-115 (2018). (doi.org/10.1016/j.reth.2018.08.003)

56. Tetsutaro Kikuchi, Masahiro Kino-oka, Masanori Wada, Toyoshige Kobayashi, Midori Kato, Shizu Takeda, Hirotsugu Kubo, Tetsuya Ogawa, Hironobu Sunayama, Kazuhito Tanimoto, Manabu Mizutani, Tatsuya Shimizu and Teruo Okano: “A novel, flexible and automated manufacturing facility for cell-based health care products: Tissue Factory”, Regenerative Therapy, Vol. 9, pp. 89-99 (2018). (doi.org/10.1016/j.reth.2018.08.004)

57. Sopita Wongin, Saranatra Waikakul, Pojchong Chotiyarnwong, Wanwipa Siriwatwechakul, Masahiro Kino-oka, Mee-Hae Kim and Kwanchanok Viravaidya-Pasuwat: “Maintenance of human chondrogenic phenotype on a dendrimer-immobilized surface for an　application of cell sheet engineering”, BMC Biotechnol., Vol. 18, No. 14 (2018). (doi.org/10.1186/s12896-018-0426-1)

58. Yuma Kato, Mee-Hae Kim, and Masahiro Kino-oka: “Comparison of Growth Kinetics between Static and Dynamic Cultures of Human Induced Pluripotent Stem Cells”, J. Biosci. Bioeng., Vol. 125, No. 6, pp. 736-740 (2018). (doi:10.1016/j.jbiosc.2018.01.002)

59. Suman Chandra Nath, Tomohiro Tokura, Mee-Hae Kim, and Masahiro Kino-oka: “Botulinum Hemagglutinin–Mediated in Situ Break–up of Human Induced Pluripotent Stem Cell Aggregates for High–Density Suspension Culture”, Biotechnol. Bioeng., Vol. 115, No. 4, pp. 910-920 (2018). (doi:10.1002/bit.26526)

60. Retno Wahyu Nurhayati, Yoshihiro Ojima, Takeaki Dohda, and Masahiro Kino-oka: “Large-Scale Culture of a Megakaryocytic Progenitor Cell Line with a Single-Use Bioreactor System”, Biotechnol. Prog., Vol. 34, No. 2, pp. 362-369 (2018). (doi:10.1002/btpr.2595)

61. Takuya Yamamoto, Masaki. Yano, Yasunori Okano, and Masahiro Kino-oka: “Numerical Investigation for the Movement of Cell Colonies in Bioreactors: Stirring and Orbital Shaking Tanks”, J. Chem. Eng. Jpn., Vol. 51, No. 5, pp. 423-430 (2018). (doi:10.1252/jcej.17we112)

62. Mee-Hae Kim, Yoshifumi Matsubara, Yukako Fujinaga, and Masahiro Kino-oka: “A Simple and Robust Method for Culturing Human Induced Pluripotent Stem Cells in an Undifferentiated State Using Botulinum Haemagglutinin”, Biotechnol J., Vol. 13, No. 2, 1700387 (1-10) (2018). (doi:10.1002/biot.201700384)

63. Masashi Kagihiro, Kazuhiro Fukumori, Takuya Aoki, Umbhorn Ungkulpasvich, Manabu Mizutani, Kwanchanok Viravaidya-Pasuwat, and Masahiro Kino-oka: “Kinetic Analysis of Cell Decay during the Filling Process: Application to Lot Size Determination in Manufacturing Systems for Human Induced Pluripotent and Mesenchymal Stem Cells”, Biochem. Eng. J., Vol. 131, pp. 31–38 (2018). (doi:10.1016/j.bej.2017.11.019)

64. Mee-Hae Kim and Masahiro Kino-oka: “Bioprocessing Strategies for Pluripotent Stem Cells Based on Waddington's Epigenetic Landscape”, Trends Biotechnol., Vol. 36, No. 1, pp. 89-104 (2018). (doi:10.1016/j.tibtech.2017.10.006)

2017

65. Mee-Hae Kim, Masakazu Inamori, Masakazu Akechi, Hirohisa Abe, Yoshiki Yagi, and Masahiro Kino-oka: “Development of an Automated Chip Culture System with Integrated On-Line Monitoring for Maturation Culture of Retinal Pigment Epithelial Cells”, AIMS Bioengineering, Vol. 4, No. 4, pp. 402-417 (2017). (doi:10.3934/bioeng.2017.4.402)

66. Vytautas Galvanauskas, Vykantas Grincas, Rimvydas Simutis, Yuki Kagawa, and Masahiro Kino-oka: “Current state and perspectives in modeling and control of human pluripotent stem cell expansion processes in stirred-tank bioreactors”, Biotechnol. Prog., Vol. 33, No. 2, pp. 355-364 (2017).

67. Mee-Hae Kim, Yo Sugawara, Yukako Fujinaga, and Masahiro Kino-oka: “Botulinum hemagglutinin-mediated selective removal of cells deviating from the undifferentiated state in hiPSC colonies”, Sci. Rep., Vol. 93, No. 7 (2017).

68. Shino Yamasaki-Yashiki, Hiroshi Sawada, Masahiro Kino-oka, and Yoshio Katakura: “Analysis of gene expression profiles of Lactobacillus paracasei induced by direct contact with Saccharomyces cerevisiae through recognition of yeast mannan”, Biosci Microbiota Food Health, Vol. 36, No. 1, pp. 17-25 (2017).

69. Suman Chandra Nath, Eiji Nagamori, Masanobu Horie, and Masahiro Kino-oka: “Culture medium refinement by dialysis for the expansion of human induced pluripotent stem cells in suspension culture”, Bioproc Biosyst Eng, Vol. 40, No. 1, pp. 123-131 (2017).

70. Menglu Li, Eiji Nagamori, and Masahiro Kino-oka: “Disruption of myoblast alignment by highly motile rhabdomyosarcoma cell in tissue structure”, J. Biosci. Bioeng., Vol. 123, No. 2, pp. 259-264 (2017).

71. Suman Chandra Nath, Masanobu Horie, Eiji Nagamori, snf Masahiro Kino-oka. “Size- and time-dependent growth properties of human induced pluripotent stem cells in the culture of single aggregate”, J. Biosci. Bioeng., Vol. 124, No. 4, pp. 469-475 (2017).

72. Sopita Wongin, Yuuki Ogawa, Mee-Hae Kim, Kwanchanok Viravaidya-Pasuwat, and Masahiro Kino-oka, “Chondrogenesis and hypertrophy in response to aggregate behaviors of human mesenchymal stem cells on a dendrimer-immobilized surface”, Biotechnol. Lett., Vol. 39, No. 8, pp. 1253-1261 (2017).

73. Rie Sonoi, Mee-Hae Kim, Kenta Yamada, and Masahiro Kino-oka. “Phenotypic heterogeneity of human retinal pigment epithelial cells in passaged cell populations”, J. Biosci. Bioeng., Vol. 124, No. 2, pp. 227-233 (2017).

74. Menglu Li and Masahiro Kino-oka: “Degradation of endothelial network in disordered tumor-containing cell sheet“, J. Biosci. Bioeng., Vol. 123, No. 6, pp. 748-753 (2017).

2016

75. Yuki Kagawa and Masahiro Kino-oka: “An in silico prediction tool for the expansion culture of human skeletal muscle myoblasts”, Royal Society Open Science, 3:160500 (2016).

76. Menglu Li and Masahiro Kino-oka: “Degradation of endothelial network in disordered tumor-containing cell sheet“, J. Biosci. Bioeng. (in press).

77. Rie Sonoi, Mee-Hae Kim, and Masahiro Kino-oka: “Facilitation of uniform maturation of human retinal pigment epithelial cells through collective movement in culture”, J. Biosci. Bioeng., Vol. 121, No. 2, pp. 220-226 (2016).

78. Manabu Mizutani, Hazuki Samejima, Hiroshi Terunuma, and Masahiro Kino-oka: “Experience of contamination during autologous cell manufacturing in cell processing facility under the Japanese Medical Practitioners Act and the Medical Care Act”, Regenerative Therapy, Vol. 5, No. 4, pp. 25-30 (2016).

79. Yuuki Ogawa, Mee-Hae Kim, and Masahiro Kino-oka “Migration-driven aggregate behaviors of human mesenchymal stem cells on a dendrimer-immobilized surface direct differentiation toward a cardiomyogenic fate commitment ”, J. Biosci. Bioeng., Vol. 122, No. 5, pp. 627-632 (2016).

80. 金美海:　“幹細胞の足場タンパク発現制御に基づく分化誘導プロセスの開発”，生物工学会誌，94巻, 3号, pp. 117-123 (2016).

2015

81. Rie Sonoi, Mee-Hae Kim, and Masahiro Kino-oka: “Facilitation of uniform maturation of human retinal pigment epithelial cells through collective movement in culture”, J. Biosci. Bioeng. (in press).

82. Yuuki Ogawa, Mee-Hae Kim, and Masahiro Kino-oka: “Changes in Human Mesenchymal Stem Cell Behaviors on Dendrimer-Immobilized Surfaces due to Mediation of Fibronectin Adsorption and Assembly”, J. Biosci. Bioeng. (in press).

2014

83. Mee-Hae Kim and Masahiro Kino-oka: “Switching between self-renewal and lineage commitment of human induced pluripotent stem cells via cell-substrate and cell-cell interactions on a dendrimer-immobilized surface”, Biomaterials, Vol. 35, No. 22, pp. 5670-5678 (2014).

84. Mee-Hae Kim, Eri Masuda, and Masahiro Kino-oka: “Kinetic analysis of deviation from the undifferentiated state in colonies of human induced pluripotent stem cells on feeder layers”, Biotechnol. Bioeng., Vol. 111, No. 6, pp. 1128-1138 (2014).

85. Mee-Hae Kim, Yuuki Ogawa, Koji Yamada, Masahito Taya, and Masahiro Kino-oka: “Directed differentiation of human mesenchymal stem cells toward a cardiomyogenic fate commitment through formation of cell aggregates”, Biochem. Eng. J., Vol. 84, pp. 53-58 (2014).

86. Eiji Nagamori, Masashi Oda, Tadashi Nakamura, Tatsuya Shimizu, Teruo Okano, and Masahiro Kino-oka: “Spatial habitation of heterogeneous cell population in a multi-layered myoblast sheet due to the differences in their behaviors of migration and cell-cell connection”, Current Nanoscience. Vol. 10, pp. 173-178 (2014).

87. Mee-Hae Kim and Masahiro Kino-oka: “Maintenance of undifferentiated state of human induced pluripotent stem cells through cytoskeleton-driven force acting to secreted fibronectin on a dendrimer-immobilized surface”, J. Biosci. Bioeng., Vol. 118, No. 6, pp. 716-722 (2014).

88. Trung Xuan Ngo, Eiji Nagamori, Tatsuya Shimizu, Teruo Okano, Masahito Taya, and Masahiro Kino-oka: “In vitro models for angiogenesis research: a review”, International Journal of Tissue Regeneration, Vol. 5, pp. 37-45 (2014).

89. Rie Sonoi, Mee-Hae Kim, and Masahiro Kino-oka; “Locational Heterogeneity of Maturation by Changes in Migratory Behaviors of Human Retinal Pigment Epithelial Cells in Culture”, J. Biosci. Bioeng., Vol. 119, No. 1, pp. 107-112 (2014).

90. Mee-Hae Kim, Yoshiko Sawada, Masahito Taya, and Masahiro Kino-oka, “Influence of Surface Topography on the Human Epithelial Cell Response to Micropatterned Substrates with Convex and Concave Architectures”, J. Biol. Eng., Vol. 8, 13 (2014).

91. Mee-Hae Kim and Masahiro Kino-oka; “Maintenance of an Undifferentiated State of Human Induced Pluripotent Stem Cells through Migration-Dependent Regulation of the Balance between Cell-Cell and Cell-Substrate Interactions”, J. Biosci. Bioeng., Vol. 119, No. 6, pp. 617-622 (2014).

2013

92. Trung X Ngo, Eiji Nagamori, Tetsutaro Kikuchi, Tatsuya Shimizu, Teruo Okano, and Masahiro Kino-oka: “Endothelial cell behavior inside myoblast sheets with different thickness”, Biotechnol. Letter, Vol. 35, No. 7, pp. 1001-1008 (2013).

93. Masrina Mohd Nadzir, Masahiro Kino-oka, Katsura Sugawara, and Masahito Taya: “Modulation of chondrocyte migration and aggregation by insulin-like growth factor-1 in cultured cartilage”, Biotechnol. Letter, Vol. 35, No. 2, pp. 295-300 (2013).

94. Eiji Nagamori, Trung X Ngo, Yasunori Takezawa, Atsuhiro Saito, Yoshiki Sawa, Tatsuya Shimizu, Teruo Okano, Masahito Taya, and Masahiro Kino-oka: “Network formation through active migration of human vascular endothelial cells in a multilayered skeletal myoblast sheet”, Biomaterials, Vol. 34, pp. 662-668 (2013).

95. Masahiro Kino-oka, Jongpill Kim, Kazue Kurisaka, and Mee-Hae Kim: “Preferential growth of skeletal myoblasts and fibroblasts in co-culture on a dendrimer-immobilized surface”, J. Biosci. Bioeng., Vol. 115, No. 1, pp. 96-99 (2013).

2012

96. Masrina Mohd Nadzir, Masahiro Kino-oka, Katsura Sugawara, and Masahito Taya: “Effect of Preservation Conditions of Collagen Substrate on Its Fibril Formation and Rabbit Chondrocyte Morphology”, J. Biosci. Bioeng., Vol. 114, No. 3, pp. 360-363 (2012).

97. Mee-Hae Kim, Rie Sonoi, Kenta Yamada, Masakazu Inamori, and Masahiro Kino-oka: “Analysis of Locality of Early-Stage Maturation in Confluent State of Human Retinal Pigment Epithelial Cells”, J. Biosci. Bioeng., Vol. 113, No. 6, pp. 778-781 (2012).

98. Masahiro Kino-oka, Trung Xuan Ngo Eiji Nagamori, Yasunori Takezawa, Yasuki Miyake, Yoshiki Sawa, Atsuhiro Saito, Tatsuya Shimizu, Teruo Okano, and Masahito Taya: “Evaluation of Vertical Cell Fluidity in a Multilayered Sheet of Skeletal Myoblasts”, J. Biosci. Bioeng., Vol. 113, No. 1, pp. 128-131 (2012).

2011

99. Shohreh Mashayekhan, Mee-Hae Kim, Masahiro Kino-oka, Jun-ichi Miyazaki and Masahito Taya: “Embryonic stem cells maintain an undifferentiated state on dendrimer-immobilized surface with D-glucose display”, Polymers, Vol. 3, pp. 2078-2087 (2011).

100. Masrina Mohd Nadzir, Masahiro Kino-oka, Nao Maruyama, Yasuaki Sato, Mee-Hae Kim, Katsura Sugawara, and Masahito Taya: “Comprehension of Terminal Differentiation and Dedifferentiation of Chondrocytes during Passage Cultures”, J. Biosci. Bioeng., Vol. 112, No. 4, pp. 395-401 (2011).

101. Mee-Hae Kim, Naoki Tsubakino, Shogo Kagita, Masahito Taya, and Masahiro Kino-oka: “Characterization of Spatial Cell Distribution in Multilayer Sheet of Human Keratinocytes through a Stereoscopic Cell Imaging System”, J. Biosci. Bioeng., Vol. 112, No. 3, pp. 289-291 (2011).

102. Yoshio Katakura, Churairat Moukamnerd, Satoshi Harashima, and Masahiro Kino-oka: “Strategy for Preventing Bacterial Contamination by Adding Exogeneous Ethanol in Solid-State Semi-Continuous Bioethanol Production”, J. Biosci. Bioeng., Vol. 111, No. 3, pp. 343-345 (2011).

2010

103. Mee-Hae Kim, Masahiro Kino-oka, and Masahito Taya: “Designing Culture Surfaces Based on Cell Anchoring Mechanisms to Regulate Cell Morphologies and Functions”, Biotechnol. Adv., Vol. 28, No. 1, pp. 7–16 (2010).

104. Mee-Hae Kim, Masahiro Kino-oka, Atsuhiro Saito, Yoshiki Sawa, and Masahito Taya: “Myogenic Induction of Human Mesenchymal Stem Cells by Culture on Dendrimer-Immobilized Surface with D-Glucose Display”, J. Biosci. Bioeng., Vol. 109, No. 1, pp. 55–61 (2010).

105. Shiplu Roy Chowdhury, Yuichi Muneyuki, Yasunori Takezawa, Masahiro Kino-oka, Atsuhiro Saito, Yoshiki Sawa, and Masahito Taya: “Growth and Differentiation Potentials in Confluent State of Culture of Human Skeletal Muscle Myoblasts”, J. Biosci. Bioeng., Vol. 109, No. 3, pp. 310–313 (2010).

106. Masahiro Kino-oka, Shogo Kagita, Masrina Mohd Nadzir, Hirofumi Inoue, Katsura Sugawara, and Masahito Taya: “Direct Measurement of Oxygen Concentration inside Cultured Cartilage for Relating to Spatial Growth of Rabbit Chondrocytes”, J. Biosci. Bioeng., Vol. 110, No. 3, pp. 363–366 (2010).

107. Churairat Moukamnerd, Masahiro Kino-oka, Minetaka Sugiyama, Yoshinobu Kaneko, Chuenchit Boonchird, Satoshi Harashima, Hideo Noda, Kazuaki Ninomiya, Suteaki Shioya, and Yoshio Katakura: “Ethanol Production from Biomass by Repetitive Solid-Sate Fed-Batch Fermentation with Continuous Recovery of Ethanol”, Appl. Microbiol. Biotechnol., Vol. 88, No. 1, pp. 87-94 (2010).

108. Mee-Hae Kim, Masahiro Kino-oka, Nao Maruyama, Atsuhiro Saito, Yoshiki Sawa, and Masahito Taya: “Cardiomyogenic Induction Of Human Mesenchymal Stem Cells By Altered Rho Family GTPase Expression On Dendrimer-Immobilized Surface With D-Glucose Display”, Biomaterials, Vol. 31, No. 30, pp. 7666-7677 (2010).

2009

109. Ali Baradar Khoshfetrat, Masahiro Kino-oka, Yasunori Takezawa, Takeyuki Yamamoto, Katsura Sugawara and Masahito Taya: “Seeding Density Modulates Migration and Morphology of Rabbit Chondrocytes Cultured in Collagen Gels”, Biotechnol. Bioeng., Vol. 102, No. 1, pp. 294-302 (2009).

110. Mee-Hae Kim, Masahiro Kino-oka, Yoshiki Morinaga, Yoshiko Sawada, Masaya Kawase, Kiyohito Yagi, and Masahito Taya: “Morphological Regulation and Aggregate Formation of Rabbit Chondrocytes on Dendrimer-Immobilized Surface with D-Glucose Display”, J. Biosci. Bioeng., Vol. 107, No. 2, pp. 196-205 (2009).

111. Masahiro Kino-oka, Yasunori Takezawa and Masahito Taya: “Quality Control of Cultured Tissues Requires Tools for Quantitative Analyses of Heterogeneous Features Developed in Manufacturing Process”, Cell and Tissue Bank, Vol. 10, No. 1, pp. 63-74 (2009).

112. Ali Baradar Khoshfetrat, Masahiro Kino-oka, Katsura Sugawara and Masahito Taya: “A Collagen-coated Surface Enables Quantitative Evaluation of Morphological Behaviors of Rabbit Chondrocytes Relating to Cell Differentiation in an Early Culture Phase”, Biochem. Eng. J., Vol. 45, No. 1, pp. 60-68 (2009).

113. Masahiro Kino-oka, Yoshikatsu Maeda, Yasuaki Sato, Nao Maruyama, Yasunori Takezawa, Ali Baradar Khoshfetrat, Katsura Sugawara and Masahito Taya: “Morphological Evaluation of Chondrogenic Potency in Passaged Cell Populations”, J. Biosci. Bioeng., Vol. 107, No. 5, pp. 544-551 (2009).

114. Shiplu Roy Chowdhury, Yuichi Muneyuki, Yasunori Takezawa, Masahiro Kino-oka, Atsuhiro Saito, Yoshiki Sawa, and Masahito Taya: “Synergic Stimulation of Laminin and Epidermal Growth Factor Facilitates the Myoblast Growth through Promoting Migration”, J. Biosci. Bioeng., Vol. 108, No. 2, pp. 174-177 (2009).

115. Masahiro Kino-oka and Masahito Taya: “Recent Developments in Processing Systems for Cell and Tissue Cultures toward Therapeutic Application”, J. Biosci. Bioeng., Vol. 108, No. 4, pp. 267–276 (2009).

116. Masahiro Kino-oka, Shiplu Roy Chowdhury, Yuichi Muneyuki, Masafumi Manabe, Atsuhiro Saito, Yoshiki Sawa, and Masahito Taya: “Automating the Expansion Process of Human Skeletal Muscle Myoblasts with Suppression of Myotube Formation”, Tissue Eng., Vol. 15, No. 4, pp. 717-728 (2009).